Magnaporthe oryzae MoPh1 perceives ER stress and promotes adaptive responses via a plasma membrane-to-vacuole pathway - PubMed
6 hours ago
- #cellular adaptation
- #ER stress
- #autophagy
- Magnaporthe oryzae MoPh1 is a plasma membrane (PM) sensor that perceives ER stress.
- MoPh1 targets autophagosome and vacuole to stimulate autophagy, aiding stress relief.
- The PM-to-vacuole pathway mediated by MoPh1 is independent of the classical ER-to-nucleus pathway.
- This pathway is crucial for alleviating ER stress and promoting cellular adaptation in fungi and plants.
- ER stress occurs due to protein misfolding or perturbations, requiring effective cellular responses.
- The study highlights the under-investigated role of the PM system in internal stress response.