Comparison of Clinical Efficiency and Safety Between Intra-Articular Injection of Platelet-Rich Plasma and Hyaluronic Acid for Hip Osteoarthritis: A Systematic Review and Meta-Analysis - PubMed
4 hours ago
- #Meta-Analysis
- #Platelet-Rich Plasma
- #Hip Osteoarthritis
- This systematic review and meta-analysis compares the efficacy and safety of intra-articular platelet-rich plasma (PRP) versus hyaluronic acid (HA) for hip osteoarthritis, involving 465 patients across seven studies.
- PRP shows a statistically significant advantage over HA in pain relief, particularly at 6 months in VAS scores (SMD = -0.38, p = 0.01), with LP-PRP and multiple injections being more effective.
- No significant differences were found between PRP and HA in improving joint function, as measured by Harris Hip Score and WOMAC-function subscore, although the WOMAC total score favored PRP overall.
- The study concludes that while PRP has moderate benefits in pain and overall symptoms, its clinical superiority is limited, warranting further high-quality research for confirmation.