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Root-knot-nematode-derived mimics of RGF peptides hijack host signalling to orchestrate feeding site formation - PubMed

3 days ago
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  • Root-knot-nematode-derived RGF-like peptides are secreted during early infection and crucial for feeding site development.
  • These nematode peptides hijack the host RGI-receptor pathway to manipulate cell proliferation and expansion in Arabidopsis and rice.
  • The PSY peptide genes, including OsPSY5 in rice, are key downstream components promoting cell elongation and facilitating nematode parasitism.
  • Cross-kingdom mimicry enables nematodes to co-opt host signaling, revealing potential targets for engineering crop resistance.