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Association of anti-DFS70 positivity with disease activity in systemic lupus erythematosus, Sjögren's syndrome, and systemic sclerosis: a cross sectional study - PubMed

4 hours ago
  • #Autoantibodies
  • #Systemic Autoimmune Diseases
  • #Disease Activity
  • Anti-DFS70 positivity rates were 23.3% in SLE, 22.5% in pSS, and 14.1% in SSc patients.
  • Univariate analysis showed anti-DFS70-positive SLE patients had lower disease activity scores and less glucocorticoid use.
  • Multivariate regression found no independent association between anti-DFS70 positivity and low disease activity in SLE, pSS, or SSc.
  • A negative correlation between anti-DFS70 titer and SLEDAI-2K in SLE was confounded by anti-dsDNA and glucocorticoid use.