M2-like GAMs secreting CSTA drive glioblastoma progression via the ITGB4-TGFB1 feedback axis - PubMed
6 hours ago
- #TGFB1
- #Glioblastoma
- #CSTA
- M2-like glioma-associated macrophages (GAMs) secrete CSTA, promoting glioblastoma progression.
- The progression is mediated via the ITGB4-TGFB1 feedback axis.
- Study involves human tissue samples and animal models with ethical approvals.
- No conflicts of interest were disclosed by the authors.
- Research funded by multiple national and provincial grants.