Incidence and Outcomes of Candida Bloodstream Infection in Solid Organ Transplant Recipients - PubMed
6 hours ago
- #Solid organ transplant
- #Mortality risk
- #Candida bloodstream infection
- Study focuses on Candida bloodstream infection (candidemia) in solid organ transplant recipients (SOTRs).
- Population-based cohort study in Ontario, Canada, with 10,249 SOTRs analyzed from 2011 to 2022.
- Candidemia occurred in 135 patients, with Candida albicans being the most frequent species (41.5%).
- Lung transplant recipients had the highest 10-year cumulative probability of candidemia at 4.17%.
- Candidemia was associated with a significant increase in mortality (adjusted hazard ratio of 6.85).
- Fluconazole-susceptible and resistant isolates both showed increased mortality risks.
- The study concludes candidemia is uncommon but associated with high mortality, especially in lung transplant recipients.