Differential Effects of Twice vs. Four Times Weekly Combined Exercise Training in Aging Adults With Hypertension: A Randomized Clinical Trial - PubMed
5 days ago
- #blood-pressure
- #hypertension
- #exercise-training
- The study compared the effects of combined resistance and aerobic training performed twice (CT2) vs. four times (CT4) per week on blood pressure in older adults with hypertension.
- Both groups exercised at the same total weekly volume (150 min/week) for 12 weeks.
- Primary outcome was 24-hour ambulatory BP; secondary outcomes included office BP and physical fitness.
- In the intention-to-treat analysis, no significant differences in BP were observed between groups, but CT4 showed reductions in office systolic (-8 mmHg) and diastolic BP (-3 mmHg).
- In the per-protocol analysis, CT4 had lower office systolic BP (-6 mmHg) than CT2 and significant reductions in 24-hour systolic (-4 mmHg) and diastolic BP (-2 mmHg).
- Cardiorespiratory fitness improved in CT4 (8%) but not in CT2.
- Higher weekly frequency (CT4) may optimize BP management, but benefits depend on high adherence.