Demographic and physiologic differences between fibrotic and non-fibrotic CT subtypes of sarcoidosis - PubMed
4 days ago
- #fibrosis
- #CT imaging
- #sarcoidosis
- Study categorizes pulmonary sarcoidosis into fibrotic, non-fibrotic, or no parenchymal abnormality based on chest CT imaging.
- Fibrotic sarcoidosis patients were older, had longer diagnosis time, and showed more severe spirometry and diffusing capacity impairments.
- Among fibrotic cases, those with a conglomerate mass were 9 times more likely to have mixed spirometric impairment.
- The study included 942 patients from two medical centers and the GRADS consortium, with 38% having fibrosis, 41% non-fibrotic abnormalities, and 21% no parenchymal issues.
- Findings suggest distinct demographic and physiologic differences in fibrotic sarcoidosis, with fibrosis subtypes linked to different lung function abnormalities.