Personalized Decision-Making in Risk-Reducing Surgery of the Ovaries - PubMed
6 hours ago
- #ovarian cancer
- #risk-reducing surgery
- #decision-making
- Study assessed factors motivating premenopausal women at familial or hereditary risk of ovarian cancer to consider risk-reducing surgery.
- Used discrete choice experiment with conjoint analysis at two cancer centers involving 355 women (median age 37 years).
- Women preferred risk-reducing salpingo-oophorectomy (RRSO) over salpingectomy (RRS) or observation.
- Osteoporosis and heart disease risks negatively influenced surgery choices, with women favoring natural menopause and milder symptoms.
- Family history of ovarian cancer increased preference for RRSO, but personal breast cancer history and genetic results were not significant.
- Findings support personalized counseling models to help women navigate complex decisions about competing risks.