Evolution patterns of posttranslational modifications in metabolic dysfunction-associated fatty liver disease: a comprehensive bibliometric analysis - PubMed
4 hours ago
- #MAFLD
- #Bibliometric Analysis
- #Posttranslational Modifications
- Metabolic dysfunction-associated fatty liver disease (MAFLD) is a major chronic liver disease and risk factor for end-stage liver disease.
- Posttranslational modifications (PTMs) play a key role in MAFLD pathogenesis by regulating lipid metabolism, inflammation, and fibrosis.
- A bibliometric analysis of 2401 publications from 2005 to 2024 reveals global research trends in PTMs related to MAFLD.
- China leads in publication output (37.6%), while the United States has the highest citation count (31,536).
- Key emerging research themes include molecular docking, ubiquitination, N6-methyladenosine, acetylation, methylation, and metabolism.
- The study highlights global collaboration patterns, research hotspots, and future directions in PTM-related MAFLD research.