Grading the evidence on the effects of exercise interventions in children and adolescents during and beyond cancer treatment: an umbrella review of systematic reviews with meta-analyses - PubMed

5 hours ago

Exercise interventions in children and adolescents during and beyond cancer treatment were reviewed.
19 systematic reviews with meta-analyses, including 53 primary studies (n=2361 participants), were analyzed.
Exercise showed significant benefits on cardiorespiratory fitness, cognitive function, and cognitive performance with moderate certainty.
Benefits were also noted in muscle strength, functional mobility, and cancer-related fatigue, but with low or very low certainty.
No significant effects were found for depression, bone mineral density, health-related quality of life, and other clinical outcomes.
The study concludes that exercise is beneficial but calls for more high-quality research to strengthen recommendations.

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