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Real-world evidence with dapagliflozin in heart failure with reduced ejection fraction in Central Eastern Europe and the Baltic region (EVOLUTION-HF CEE-BA Study) - PubMed

6 hours ago
  • #dapagliflozin
  • #heart failure
  • #real-world evidence
  • Study on real-world evidence with dapagliflozin in HFrEF patients in Central Eastern Europe and the Baltic region.
  • Multicentre, observational study across 9 countries with 1131 HFrEF patients included.
  • High persistence rates of dapagliflozin (95-96% at 6-12 months), but low optimal dosing of other guideline-directed therapies.
  • Common comorbidities included atrial fibrillation (46%), type 2 diabetes (37%), and chronic kidney disease (29%).
  • Despite treatment persistence, improvement in HF management decisions in the region is needed.