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Pancreatic adenocarcinoma nutritional-clinical index (PANCIN): A novel prognostic tool in advanced pancreatic cancer - PubMed

4 days ago
  • #nutritional index
  • #pancreatic cancer
  • #prognostic tool
  • PANCIN is a novel prognostic tool for advanced pancreatic cancer, combining clinical-nutritional and radiological features.
  • Key predictors in PANCIN include Vitamin B12 levels, Mid-Upper Arm Circumference, and Visceral Fat-to-Muscle area Ratio.
  • High-risk patients according to PANCIN had significantly shorter progression-free survival (6.2 months) and overall survival (10.4 months) compared to low-risk patients (14.1 and 19.8 months, respectively).
  • PANCIN correlates with CA19.9 levels, radiological response, infections, and severe hematologic toxicities.
  • The tool may aid in risk stratification and early nutritional support for advanced pancreatic cancer patients undergoing chemotherapy.