The Frame of Survival for Sepsis: A Practical Systems Framework for Time-Sensitive Critical Illness in Low-Resource Settings - PubMed
6 hours ago
- #low-resource-settings
- #sepsis-management
- #critical-care
- The 'Sepsis Frame of Survival' is a practical framework designed to improve sepsis management in low-resource settings (LRS).
- Sepsis causes disproportionate mortality in LRS, where many international guideline recommendations are not feasible due to resource constraints.
- The framework emphasizes high-impact, feasible actions like early recognition, timely antimicrobials, oxygen therapy, cautious fluid resuscitation, and quality improvement (QI).
- Development involved a scoping review, Delphi-style prioritization, and a consensus meeting to finalize the model and priority actions.
- The framework distinguishes between near-term feasible changes and long-term system investments, highlighting the need for locally generated evidence.
- Key components include triage, diagnostics where feasible, source control, and referral systems.
- The initiative was convened by the Society of Critical Care Medicine and involved a multidisciplinary task force.
- The framework aligns with broader emergency and essential critical care system strengthening in LRS.