Procedure time and clinical outcomes after thrombectomy: a pooled cohort analysis of three randomised trials - PubMed
4 hours ago
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- #stroke outcomes
- #endovascular thrombectomy
- Longer procedure time (PT) during endovascular thrombectomy (EVT) is associated with worse clinical outcomes in acute ischemic stroke.
- Each 10-minute increase in PT reduces the probability of a favorable outcome (mRS 0-2) by 1.52% and increases mortality by 0.77%.
- Compared to PT ≤ 60 minutes, PT of 60-120 minutes and >120 minutes significantly lowers odds of favorable outcomes and raises mortality.
- Longer PT is also linked to higher rates of symptomatic intracranial hemorrhage (sICH).
- Total passes and first pass effect (FPE) explain only a small portion (about 12%) of the association between PT and outcomes.
- The findings highlight the importance of minimizing intraprocedural delays to improve EVT outcomes.