High-Flow or Standard Oxygen in Acute Hypoxemic Respiratory Failure - PubMed
5 hours ago
- #respiratory failure
- #oxygen therapy
- #clinical trial
- Study compares high-flow nasal cannula oxygen therapy vs. standard oxygen therapy in acute hypoxemic respiratory failure.
- Primary outcome: No significant difference in 28-day mortality between high-flow (14.6%) and standard oxygen (14.6%) groups.
- Secondary outcome: High-flow oxygen showed a lower intubation rate (42.4%) compared to standard oxygen (48.4%).
- Serious adverse events were slightly higher in the high-flow oxygen group (2.3%) vs. standard oxygen (1.1%).
- Conclusion: High-flow oxygen did not reduce 28-day mortality but may reduce intubation rates in acute hypoxemic respiratory failure.