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Global burden of enteric infectious diseases, diarrhoeal diseases, and corresponding aetiologies, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023 - PubMed

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  • #Diarrhoeal diseases
  • #Enteric infectious diseases
  • #Global burden of disease
  • The study systematically analyzed the global burden of enteric infectious diseases from 1990 to 2023.
  • In 2023, enteric infectious diseases caused 1.27 million deaths globally, a significant decrease from 3.69 million in 1990.
  • Diarrhoeal diseases accounted for most deaths in 2023 (1.11 million), followed by enteric fever and invasive non-typhoidal Salmonella infections.
  • South Asia and sub-Saharan Africa were the most affected regions, with 599,000 and 501,000 deaths respectively.
  • Rotavirus was the leading cause of diarrhoeal disease deaths globally (16.3%), particularly in children under 5 (40.2%).
  • 141 out of 204 countries met the GAPPD mortality target (<20 deaths per 100,000 children under 5) in 2023.
  • Astrovirus and sapovirus, newly included pathogens, caused 24,600 and 18,800 deaths respectively in 2023.
  • Despite declining mortality rates, sustained efforts are needed to address the persistent burden, especially in high-risk regions.