Management and Outcome of Failed Transcatheter Tricuspid Edge-to-Edge Repair: Insights From the FATE International Registry - PubMed
5 hours ago
- #T-TEER failure
- #tricuspid regurgitation
- #cardiac reintervention
- The FATE International Registry analyzed device-related failures after transcatheter tricuspid edge-to-edge repair (T-TEER) in 2,278 procedures.
- Device failure occurred in 5.4% of cases, with single-leaflet device attachment being the most common mechanism (75%), followed by loss of leaflet insertion (24%) and embolization (1%).
- Management included medical therapy in 54% and reintervention in 46%, with reintervention leading to greater tricuspid regurgitation reduction and right atrial reverse remodeling.
- Despite reintervention benefits, the composite endpoint of death or heart failure rehospitalization was frequent (38.2%) and did not differ significantly between medical therapy and reintervention strategies over a median follow-up of 255 days.
- Higher TRI-SCORE, acute kidney injury, and greater discharge tricuspid regurgitation severity independently predicted adverse outcomes, highlighting the clinical relevance of device failure.