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Hypertensive Disorders of Pregnancy: A Systematic Review of International Clinical Practice Guidelines - PubMed

12 hours ago
  • #systematic review
  • #clinical practice guidelines
  • #hypertensive disorders of pregnancy
  • Systematic review updates a 2020 analysis of clinical practice guidelines (CPGs) for hypertensive disorders of pregnancy (HDPs).
  • Searches conducted in EMBASE, MEDLINE, and Cochrane Central Register of Controlled Trials from January 2015 to January 2025.
  • Included 23 CPGs (15 updates, 8 new) in English, Dutch, French, German, Norwegian, or Spanish.
  • AGREE-II tool used for guideline assessment; half scored 'clinically useful', half 'useful with modifications'.
  • Greater consistency in recommending antihypertensive treatment for non-severe hypertension in women with chronic hypertension.
  • Improved guidance on maternal and fetal monitoring for preeclampsia risk or diagnosis.
  • Aspirin dosage for preeclampsia prevention now more consistent (75-162 mg/d).
  • Persistent inconsistencies in defining 'severe' preeclampsia, timing of birth for preterm preeclampsia, and aspirin specifics.
  • Need for auditable standards and further research to address discrepancies and optimize pregnancy outcomes.