The role of neuroactive steroids in psychiatric and neurological disorders: Neurobiology and therapeutic perspectives - PubMed
11 hours ago
- #psychiatric-disorders
- #neurological-disorders
- #neuroactive-steroids
- Neuroactive steroids are key modulators of brain physiology and pathology.
- They influence neural function by acting on specific neuronal receptors.
- These steroids are involved in neurotransmitter systems, the HPA axis, and neuroinflammatory pathways.
- Linked to psychiatric and neurological disorders like depression, schizophrenia, and Alzheimer's disease.
- Potential therapeutic opportunities include drugs like zuranolone and ganaxolone.
- Challenges remain in optimizing delivery and receptor specificity for treatments.