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Methods of skeletal age assessment using hand and wrist radiographs in children and their applicability across different ethnicities: systematic review and meta-analysis protocol - PubMed

3 hours ago
  • #Ethnicity in Medicine
  • #Pediatric Radiology
  • #Skeletal Age Assessment
  • Skeletal age assessment via hand and wrist radiographs evaluates biological maturity in children, especially when chronological age is unknown.
  • Differences in skeletal maturity exist among ethnicities due to internal and external factors, raising questions about the applicability of current international references.
  • A systematic review and meta-analysis will be conducted using PubMed, Scopus, Web of Science, EMBASE, and Ovid to assess the applicability of these methods across ethnicities.
  • Study selection and data extraction will involve Covidence software, independent reviewers, and a PRISMA flow diagram, with quality assessed via the JBI critical appraisal tool.
  • The review aims to analyze existing literature, highlight knowledge gaps, and explore ethnic differences to potentially develop population-specific reference standards.