Prevention of oral mucositis in patients undergoing cancer chemotherapy using betamethasone mouthwash: A multicenter randomized controlled trial protocol - PubMed
5 hours ago
- #Oral Mucositis
- #Randomized Controlled Trial
- #Chemotherapy
- A Phase II multicenter RCT will evaluate betamethasone mouthwash versus sodium gualenate hydrate mouthwash for preventing chemotherapy-induced oral mucositis.
- The primary outcome is to assess the prevention of Grade 1 oral mucositis using CTCAE v3.0 and v5.0.
- Secondary outcomes include evaluating the prevention of higher-grade mucositis, oral candidiasis incidence, and chemotherapy completion rates.
- This study aims to enhance cancer patients' quality of life by establishing an effective preventive strategy.
- The trial is registered with the Japan Registry of Clinical Trials.