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Small Bites vs Large Bites for Closure of Abdominal Midline Incisions: A Randomized Clinical Trial - PubMed

6 hours ago
  • #Long-term Outcomes
  • #Incisional Hernia
  • #Surgical Technique
  • The small-bites fascial closure technique (5 mm × 5 mm) reduces long-term incisional hernia risk compared to large bites (10 mm × 10 mm) after elective midline laparotomy.
  • At 13-year follow-up, cumulative incisional hernia incidence was 34% for small bites vs. 49% for large bites (HR 0.61, 95% CI 0.43–0.86).
  • Hernias in the small-bites group were significantly smaller (mean width 25 mm vs. 43 mm) and less likely to exceed 20 mm (17% vs. 34%; HR 0.36, 95% CI 0.21–0.60).
  • Hernia repair rates were similar between groups, but patients with hernias reported significantly lower quality of life.
  • The study recommends small-bites closure as standard practice due to its simplicity, cost neutrality, and broad applicability.