Acceptance of recommendations by a pharmacogenetics clinic - PubMed
5 hours ago
- #Pharmacist Recommendations
- #Precision Medicine
- #Pharmacogenetics
- Study assessed acceptance of genotype-based pharmacist recommendations in a pharmacogenetics (PGx) clinic.
- Retrospective chart review of 201 patients seen between 2017 and 2022, focusing on CYP2D6/CYP2C19 and drug classes like opioids, SSRIs, and PPIs.
- 50% of prescriptions were discordant at baseline, decreasing to 22% at 3 months, showing a 56% acceptance rate of recommendations.
- SSRIs showed a 64% discordance at baseline, reduced to 25% at 3 months, with a 61% acceptance rate.
- PPIs had a 42% discordance at baseline, dropping to 10% at 3 months, with a 76% acceptance rate.
- Significant reduction in discordant gene-drug pairs was observed, indicating effective acceptance of PGx pharmacist recommendations.