Hepatic Outcomes in Lean Versus Nonlean Metabolic Dysfunction-Associated Steatotic Liver Disease: Propensity-Matched Cohort Study - PubMed
5 hours ago
- #Liver Disease
- #BMI
- #MASLD
- Study compares hepatic outcomes between lean (BMI <25) and nonlean (BMI ≥25) MASLD patients.
- Lean MASLD patients showed higher risks of fibrosis, cirrhosis, HCC, and mortality than nonlean counterparts.
- Predictors of adverse outcomes in lean MASLD include older age, diabetes, hypoalbuminemia, thrombocytopenia, and elevated AST.
- Current obesity-centered screening paradigms may under-serve lean MASLD patients, who are at higher risk.
- The study advocates for revised screening protocols to include lean individuals for better disease management.