Chronotherapy to reinforce circadian rhythms improves poststroke outcomes and glymphatic function in mice - PubMed
6 hours ago
- #Stroke Recovery
- #Chronotherapy
- #Glymphatic Function
- Chronotherapy interventions such as KL001, high-dose melatonin, light pulses, and time-restricted feeding enhance glymphatic function in mice.
- Initiating KL001 or time-restricted feeding three days post-stroke improves motor outcomes, reduces lesion volume, and lowers brain cytokine burden in mice.
- Reinforcing circadian rhythms after stroke can significantly boost neurological recovery, even with delayed treatment onset.