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Effect of noninvasive brain stimulation for unilateral spatial neglect after stroke: a systematic review and meta-analysis - PubMed

5 hours ago
  • #stroke rehabilitation
  • #noninvasive brain stimulation
  • #unilateral spatial neglect
  • Noninvasive brain stimulation (NIBS) interventions, including rTMS, TBS, tDCS, and tACS, were evaluated for treating unilateral spatial neglect (USN) after stroke.
  • rTMS showed significant improvements in line bisection test (LBT), star cancellation test (SCT), and Catherine Bergego scale (CBS) outcomes.
  • TBS significantly improved SCT and CBS scores, while tDCS showed moderate benefits for LBT and SCT, but tACS did not demonstrate significant effects compared to controls.
  • Subgroup analysis indicated that intervention timing and protocol type moderated NIBS effects, with acute phase interventions and excitatory protocols on the ipsilesional posterior parietal cortex yielding greater therapeutic potential.
  • The systematic review and meta-analysis concluded that rTMS and TBS offer higher therapeutic potential than tDCS and tACS for reducing USN severity and improving daily living activities.