Outcomes of Functional Substrate Mapping Based Ablation in Addition to Pulmonary Vein Isolation in Atrial Fibrillation - PubMed
6 hours ago
- #Substrate Mapping
- #Catheter Ablation
- #Atrial Fibrillation
- FSM using ILAM identifies deceleration zones (DZs) as slow conduction areas critical in AF.
- Study of 206 AF patients: DZ(+) group had additional ablation targeting DZs along with PVI, while DZ(-) group had PVI alone.
- DZs were colocalized with inducible atrial tachycardia critical isthmuses in 81.4% of cases.
- Arrhythmia-free survival was higher in DZ(-) patients than DZ(+) at 12.5 months follow-up.
- Presence of DZ was the sole independent predictor of arrhythmia recurrence (HR 2.152).
- Targeting DZs adjunct to PVI may improve success, especially in paroxysmal AF.