Silencing of circRERE(4-5) inhibits ONECUT2-mediated tumorigenesis and metastasis in gastric cancer - PubMed
5 hours ago
- #circRERE(4-5)
- #gastric cancer
- #metastasis
- Silencing circRERE(4-5) inhibits ONECUT2-mediated tumorigenesis and metastasis in gastric cancer (GC).
- CircRERE(4-5) is highly expressed in GC tissues and cells, correlating with tumor size and metastasis.
- Knockdown of circRERE(4-5) suppresses GC cell growth and movement via miR-571 and ONECUT2 pathway.
- Antisense oligonucleotides targeting circRERE(4-5) inhibit xenograft tumor growth and spread in mice.
- CircRERE(4-5) has functional and diagnostic significance in GC progression.