Longitudinal changes in epigenetic clocks predict survival in the InCHIANTI cohort - PubMed
5 hours ago
- #mortality prediction
- #biological aging
- #epigenetic clocks
- Epigenetic clocks derived from DNA methylation patterns are promising biomarkers of biological aging.
- Longitudinal study of 699 adults from the InCHIANTI cohort followed for up to 24 years.
- Faster increases in several epigenetic clocks were linked to higher risk of death.
- Dynamic changes in epigenetic aging reflect evolving health status and may serve as sensitive indicators for interventions aimed at extending healthspan and longevity.
- The study involves patents and competing interests related to epigenetic clocks.