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Review of Potential Diagnostic and Therapeutic Developments in Systemic Lupus Erythematosus (SLE) - PubMed

6 hours ago
  • #SLE
  • #Treatment
  • #Biomarkers
  • SLE is a complex autoimmune disease affecting multiple organs, with challenges in diagnosis and treatment.
  • Autoantibodies and immune complexes contribute to vasculature accumulation and organ damage in SLE.
  • Recent research highlights promising biomarkers like PTX3 and S100A8 for early diagnosis and activity correlation.
  • Monoclonal antibodies such as belimumab and anifrolumab are FDA-approved treatments, with others in Phase II trials.
  • Advances in biomarkers and biologics aim to enable personalized, targeted therapy for improved SLE management.