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Night shift work exposure shapes neurobehavioral and cardiometabolic profiles in female healthcare workers: a cross-sectional study - PubMed

4 hours ago
  • #sleep quality
  • #night shift work
  • #cardiometabolic risk
  • Higher cumulative night shift exposure (≥500 shifts) was linked to lower physical activity, poorer sleep quality, reduced work ability, and early insulin resistance.
  • Long-term night shift exposure (11-35 years) was associated with poorer psychological well-being, higher adiposity, and increased cardiovascular risk.
  • Sleep quality was consistently affected by all night shift exposure metrics, while metabolic outcomes were more strongly tied to duration and individual factors.
  • Correlation analyses showed clustering of sleep, neurobehavioral, and cardiometabolic variables, with associations strengthening with higher exposure levels.
  • The study suggests using early subclinical indicators for precision prevention and early intervention strategies in female healthcare workers.