Cellular therapies in systemic Sclerosis: immunopathogenesis-informed precision targeting with CAR-T and CAR-NK approaches - PubMed
6 hours ago
- #CAR-T Cells
- #Systemic Sclerosis
- #Cellular Therapies
- Systemic sclerosis (SSc) is a serious autoimmune disease marked by immune issues, blood vessel problems, and excessive scarring.
- Current treatments for SSc are limited, driving interest in new cellular therapies like CAR-T and CAR-NK cells.
- CAR-T and CAR-NK therapies aim to reset the immune system, potentially offering long-term remission by targeting specific cells such as B-cells.
- Early clinical evidence and comparisons to other autoimmune diseases suggest promise, though more research is needed.