Uncovering the Independent Role of Lipid Peroxidation in Osteoporosis Through an Integrated Bibliometric and Bioinformatics Analysis - PubMed
5 hours ago
- #osteoporosis
- #bioinformatics
- #lipid peroxidation
- Study integrates bibliometric and bioinformatics analysis to explore lipid peroxidation's role in osteoporosis.
- China leads in publication volume, while the US has higher academic influence in the field.
- Lipid peroxidation identified as an emerging research frontier in osteoporosis since 2023.
- Bioinformatics analysis reveals 127 common targets between osteoporosis and lipid peroxidation, enriched in pathways like NF-κB and estrogen signaling.
- Five key targets (APP, FOXO1, FOXO3, JUN, SNCA) identified with good diagnostic efficacy for osteoporosis.
- Research provides new insights into osteoporosis mechanisms and potential targeted therapies.