Assessing the Validity and Acceptability of an Adult Quality of Life Questionnaire, the EORTC QLQ-C30, for Adolescents With Cancer - PubMed
3 hours ago
- #Adolescent Oncology
- #Psychometric Validation
- #Quality of Life Assessment
- The study conducted the first systematic evaluation of the adult EORTC QLQ-C30 questionnaire in adolescents with cancer aged 12-17, finding it acceptable and easy to complete in about 12 minutes.
- Psychometric analysis showed acceptable-to-good internal consistency (Cronbach's α 0.70-0.84) and good convergent and discriminant validity when compared with the PedsQL Cancer Teen questionnaire.
- Known-group validity was partially supported by score comparisons based on treatment intent and performance status, and over half (57%) of participants preferred paper over electronic administration.
- The research establishes the QLQ-C30 as a valid measure for use in clinical trials involving adolescents, aiding life course-based outcome assessments and addressing underrepresentation in trials.