Exploring the impact of dietary extracellular vesicles on gut health: homeostasis, barrier defense, immunity, and signaling pathways - PubMed
4 days ago
- #gut-health
- #immune-modulation
- #extracellular-vesicles
- Dietary extracellular vesicles (D-EVs) are nanoscale vesicles from edible sources that regulate gut health.
- D-EVs influence microbiota composition, intestinal barrier integrity, and immune responses.
- They modulate inflammation, immune homeostasis, and disease prevention pathways.
- Key pathways include Wnt/β-catenin, NF-κB, and STING signaling.
- D-EVs show potential as therapeutic agents in gastrointestinal disorders.
- Challenges include standardization, large-scale production, and long-term safety.
- Advances in D-EV engineering and AI optimization are highlighted.
- Potential applications in functional food development for gut health.