Changes in Epidemiology of Candidemia in the United States with a Focus on Candida auris - PubMed
3 hours ago
- #Candida auris
- #Candidemia Epidemiology
- #Antifungal Resistance
- Candidemia incidence in the US increased from 2015 to 2024, with overall 30-day mortality rising from 24.7% to 31.8%.
- The proportion of Candida albicans cases decreased, while Candida auris cases increased significantly.
- Patients with C. auris candidemia were more likely to be Black, have renal failure, and have a higher Social Vulnerability Index.
- Fluconazole resistance increased notably in C. parapsilosis (from 2.5% to 10.8%) and C. tropicalis (from 6.2% to 18.1%).
- The study highlights concerning nationwide trends, including rising mortality and shifts in Candida species and antifungal resistance.