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Waking up to the truth: Associations between sleep disorders and multidomain functional outcomes in Alzheimer's disease - PubMed

5 hours ago
  • #Alzheimer's disease
  • #cognitive impairment
  • #sleep disorders
  • Sleep disorders are common in older adults and linked to cognitive dysfunction in Alzheimer's disease (AD).
  • A study of 10,823 participants found significant associations between sleep disorders and greater cognitive impairment and poorer instrumental activities of daily living (IADL) performance in AD patients.
  • Cognitive impairment mediated about 62% of the association between sleep disorders and IADL difficulties, indicating a substantial indirect effect.
  • The findings suggest that screening and managing sleep problems could be valuable in comprehensive care strategies for AD patients.