Integrative Oncology for Biochemical Recurrence of Epithelial Ovarian Cancer - PubMed
6 days ago
- #Integrative Oncology
- #Biochemical Recurrence
- #Ovarian Cancer
- Biochemical recurrence of epithelial ovarian cancer (EOC) involves rising CA-125 levels without clinical or radiologic evidence of disease.
- Cytotoxic therapy at this stage does not improve survival and may reduce quality of life.
- Integrative oncology (IO) interventions can support women during biochemical recurrence.
- Mind-body therapies (e.g., mindfulness, yoga, cognitive behavioral therapy) reduce anxiety, distress, and fear of recurrence.
- Exercise and acupuncture improve vitality, mood, and sleep.
- Nutritional strategies (anti-inflammatory diets, vitamin D, omega-3 fatty acids) promote resilience and overall health.
- Natural compounds (green tea, medicinal mushrooms, modified citrus pectin, melatonin, AHCC) show immune-modulating or anti-tumor effects in preclinical studies.
- Metformin, a repurposed non-oncologic drug, has strong rationale, especially for women with type 2 diabetes.
- IO approaches are safe, feasible, and evidence-informed, improving quality of life and potentially influencing disease biology.