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Potential of chimeric antigen receptor (CAR) T cell immunotherapy in systemic lupus erythematosus (SLE) - PubMed

7 hours ago
  • #CAR T-cell therapy
  • #Autoimmune disease treatment
  • #Systemic lupus erythematosus
  • CAR T-cell therapy shows potential as a novel treatment for systemic lupus erythematosus (SLE), offering more effective and potentially curative options.
  • The treatment landscape for SLE is transforming as of 2025, driven by innovative immunotherapies that target autoimmune dysregulation.
  • Research on CAR T-cell therapy in SLE explores mechanisms, challenges, and future directions, with targets like BCMA, CD19, and CD22 being investigated.
  • SLE is a chronic autoimmune disease with multiorgan inflammation, where conventional therapies often face resistance and significant side effects.