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2024-2025 COVID-19 mRNA Vaccine Effectiveness against Severe Disease - PubMed

6 hours ago
  • #mRNA Vaccine
  • #Vaccine Effectiveness
  • #COVID-19
  • Study evaluated the effectiveness of the 2024-2025 COVID-19 mRNA vaccine against severe disease.
  • Used electronic health records from a South Carolina health system for analysis.
  • Matched vaccinated and unvaccinated individuals based on demographic and clinical factors.
  • Vaccine effectiveness was 41.3% against emergency department visits or more severe care.
  • Effectiveness was 46.1% against hospitalization.
  • Demonstrated moderate protection in a population with high prior exposure.
  • Highlighted the need for increased vaccination coverage, especially among high-risk groups.