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Integrated single-cell and spatial transcriptomic profiling decodes lineage plasticity and immune microenvironment remodeling in prostate cancer progression - PubMed

5 hours ago
  • #Transcriptomics
  • #Immune Microenvironment
  • #Prostate Cancer
  • Study focuses on lineage plasticity and immune microenvironment remodeling in prostate cancer progression using integrated single-cell and spatial transcriptomic profiling.
  • Ethical approvals were obtained from China Medical University Institutional Review Board and Animal Care and Use Committee, complying with Helsinki declaration, ARRIVE guidelines, and other international standards.
  • Authors declare no competing interests.
  • References include global and regional studies on prostate cancer incidence, mortality, and treatment strategies.