Elastance as a determinant of the effect of prone positioning on mortality in acute respiratory distress syndrome: a post hoc analysis of the PROSEVA trial - PubMed
a day ago
- #Respiratory Mechanics
- #Acute Respiratory Distress Syndrome
- #Prone Positioning
- Prone positioning's effect on 90-day mortality in ARDS patients does not meaningfully depend on baseline respiratory system elastance (Ers).
- Higher baseline Ers is linked to greater improvements in driving pressure (DPrs) during prone positioning, but this change does not correlate with reduced mortality.
- The analysis uses Bayesian modeling on PROSEVA trial data, concluding that elastance should not guide prone positioning decisions for mortality benefit.