Efficacy of 0.01% atropine eye drops for myopia control in children of different ethnicities: a systematic review and meta-analysis - PubMed
5 hours ago
- #myopia control
- #atropine eye drops
- #ethnic differences
- 0.01% atropine eye drops effectively slow myopia progression in children across different ethnicities.
- The efficacy of 0.01% atropine varies by ethnicity, with the greatest reduction in myopia progression observed in South Asian populations (66% reduction).
- East Asian populations showed a 35% reduction in myopia progression, while white populations showed a 28% reduction.
- The meta-analysis included 25 randomized clinical trials (RCTs) with 4374 children aged 4-18.
- 0.01% atropine slowed myopia progression by 0.21D per year compared to the placebo group.
- Similar efficacy patterns were observed in slowing ocular axial length (AL) elongation.
- Clinical practice should consider ethnic differences to optimize treatment effects.