Implementation of CAR-T cell therapy in outpatient settings: a critical review of current literature regarding health outcomes, benefits, challenges, and future directions - PubMed
5 hours ago
- #cancer immunotherapy
- #CAR-T therapy
- #outpatient oncology
- CAR-T cell therapy is transforming treatment for hematologic malignancies, with a shift from inpatient to outpatient settings.
- Outpatient CAR-T therapy requires careful patient selection, robust monitoring, and rapid response protocols to match inpatient safety and efficacy.
- Key side effects like Cytokine Release Syndrome (CRS) and Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS) are major concerns in outpatient settings.
- Outpatient administration reduces healthcare costs, improves resource allocation, and enhances patient psychological well-being.
- Challenges include the need for comprehensive support strategies, specialized teams, and equitable access to ensure safety and effectiveness.
- Future directions include advancements in CAR-T product design and remote monitoring technologies to standardize outpatient care.