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Antiviral chewing gum to reduce influenza and herpes simplex virus transmission

a year ago
  • #public health
  • #infectious diseases
  • #antiviral research
  • Infectious diseases like coronavirus, H1N1, SARS, Ebola, Zika, and H5N1 pose significant global health and economic threats.
  • Seasonal influenza causes substantial disease burden and economic losses, exceeding $11.2 billion annually in the U.S.
  • HSV-1 infects over two-thirds of the global population and is a leading cause of infectious blindness in Western countries.
  • Low vaccination rates and lack of HSV vaccines highlight the need for new approaches targeting viral transmission sites.
  • Researchers developed a chewing gum from lablab beans containing antiviral protein FRIL to neutralize HSV and influenza viruses.
  • The gum reduced viral loads by over 95%, similar to results seen in SARS-CoV-2 studies.
  • The gum was prepared as a clinical-grade drug product and found to be safe for human use.
  • Researchers are exploring lablab bean powder to combat bird flu (H5N1), which has affected 54 million birds recently.
  • Bean powder has previously shown effectiveness against H5N1 and H7N9, and is being tested in bird feed.
  • The study highlights the potential of FRIL protein in natural food products to prevent viral infection and transmission.