Antiviral chewing gum to reduce influenza and herpes simplex virus transmission
a year ago
- #public health
- #infectious diseases
- #antiviral research
- Infectious diseases like coronavirus, H1N1, SARS, Ebola, Zika, and H5N1 pose significant global health and economic threats.
- Seasonal influenza causes substantial disease burden and economic losses, exceeding $11.2 billion annually in the U.S.
- HSV-1 infects over two-thirds of the global population and is a leading cause of infectious blindness in Western countries.
- Low vaccination rates and lack of HSV vaccines highlight the need for new approaches targeting viral transmission sites.
- Researchers developed a chewing gum from lablab beans containing antiviral protein FRIL to neutralize HSV and influenza viruses.
- The gum reduced viral loads by over 95%, similar to results seen in SARS-CoV-2 studies.
- The gum was prepared as a clinical-grade drug product and found to be safe for human use.
- Researchers are exploring lablab bean powder to combat bird flu (H5N1), which has affected 54 million birds recently.
- Bean powder has previously shown effectiveness against H5N1 and H7N9, and is being tested in bird feed.
- The study highlights the potential of FRIL protein in natural food products to prevent viral infection and transmission.