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Inclisiran safety and efficacy in real-world clinical practice: results of a retrospective observational investigation - PubMed

5 hours ago
  • #hypercholesterolemia
  • #PCSK9i
  • #LDL-C
  • Inclisiran significantly reduces LDL-C levels by 59.5% with statin ± ezetimibe and 56% without.
  • Higher likelihood of achieving LDL-C <55 mg/dl when inclisiran is used with statins ± ezetimibe.
  • Adverse effects were mild, occurring in 5.8% of patients.
  • Study confirms inclisiran as a well-tolerated and potent LDL-C-lowering treatment.
  • Greater efficacy observed when inclisiran is combined with statins ± ezetimibe.