Traditional, central obesity, and metabolic indices: which metrics better reflect osteoarthritis risk? A cross-sectional study in U.S. adults - PubMed
5 hours ago
- #obesity indices
- #NHANES
- #osteoarthritis
- Obesity is a major risk factor for osteoarthritis (OA), but traditional metrics like BMI may not fully capture OA risk.
- The study compared 10 obesity indices across general, abdominal, and metabolic categories to identify the best indicators for OA risk.
- Abdominal indices WWI and C-index showed higher discriminative capacity for OA risk than BMI and metabolic indices.
- WWI and C-index were associated with significantly higher OA odds in the highest tertiles compared to the lowest.
- Nonlinear relationships were observed, with steeper risk gradients beyond specific WWI and C-index cutoffs.
- Central adiposity indices (WWI, C-index) demonstrated stronger associations with OA prevalence than traditional and metabolic metrics.
- Combining BMI with WWI or C-index may improve OA risk profiling in research settings.