- COVID-19 is far worse than seasonal flu, with significant mortality and strain on healthcare systems.
- Social distancing, hand washing, and coughing hygiene are effective measures to slow the spread.
- Warmer weather may slightly reduce transmission but strong measures are still necessary.
- Masks can reduce virus spread from asymptomatic carriers, but clear public messaging is essential.
- Risk factors include older age, hypertension, obesity, and smoking; more data needed.
- Several drugs (e.g., remdesivir, hydroxychloroquine) show promise but lack solid evidence; trials are ongoing.
- Monoclonal antibodies and convalescent sera are being investigated as treatments.
- Multiple vaccines are in development, but none yet proven in humans; mRNA vaccines show potential.
- Countries like China, South Korea have shown that strict measures can suppress local transmission.
- Testing limitations: PCR detects viral RNA, serology tests detect antibodies but have time lag.
- Reinfection appears unlikely in short term; immunity development is normal but duration unknown.
- Ibuprofen/NSAIDs safety uncertain; paracetamol is recommended until more data.
- Post-lockdown control may rely on testing, contact tracing, masks, and possibly seasonality.
- Many open questions remain about superspreading, children's role, and country-specific lethality.