Stanford Scientists Successfully Reverse Autism Symptoms in Mice
3 days ago
- #epilepsy
- #neuroscience
- #autism
- Overactivity in the reticular thalamic nucleus causes autism-like behaviors in mice.
- Drugs reducing this activity reversed symptoms, including seizure susceptibility and social deficits.
- The reticular thalamic nucleus filters sensory information between the thalamus and cortex.
- Shared pathways with epilepsy suggest overlapping mechanisms in autism and epilepsy.
- Experimental drugs like Z944 and DREADD-based neuromodulation reversed behavioral deficits in mice.
- Epilepsy is 30 times more prevalent in people with autism than in the general population.
- The study highlights the reticular thalamic nucleus as a novel treatment target for autism.